Detailed Information
Full Name HAYASHI Hideki Date of Birth 1958/11
Affiliation Institute of Biomedical Sciences 
TEL +81-95-849-7047 FAX +81-95-849-7048
Job Title Associate Professor Academic Degrees /
Medical doctor(1983/05)
Education 1983/03¸Nagasaki University¸Faculty of Medicine¸Graduated
1989/03¸Osaka University¸Graduate School, Division of Medicine¸Doctor Course¸Accomplised credits for doctoral program
Employment Experience 2001/04 - 2004/10¸Nagasaki University¸School of Medicine¸Research Associate
2004/11 - 2007/03¸Nagasaki University¸Graduate School of Biomedical Sciences¸Graduate School of Biomedical Science¸Lecturer
2007/04 - *¸Nagasaki University¸Graduate School of Biomedical Sciences¸Infection Research¸Associate Professor
Specialties General medical chemistry
Academic Societies
Committee Memberships
Ongoing Joint Research
Technical Supervision
Technical Consulting
Themes for Prospective Joint Research
Themes for Ongoing Research Roles of Interferon-regulatory factors in Immunity and Oncogenesis
Cloning of Apoptosis-associated Molecules
Research Themes in the Past
Literary Works, Books, Writings and Research Papers, Art Works, Industrial Products, Software, Sports Records, etc.
1 Hayashi H, Kubo Y, Izumida M, Takahashi E, Kido H, Sato K, Yamaya M, Nishimura H, Nakayama K, Matsuyama T:Enterokinase enhances Influenza A virus infection by activating trypsinogen in human cell lines.¸Front. Cell. Infect. Microbiol.¸8.91-¸2018/03
2 Kubo Y, Masumoto H, Izumida M, Kakoki K, Hayashi H, Matsuyama T:Rab3a-Bound CD63 Is Degraded and Rab3a-Free CD63 Is Incorporated into HIV-1 Particles. ¸Front Microbiol.¸8.1653-¸2017/08
3 Kubo Y, Izumida M, Yashima Y, Yoshii-Kamiyama H, Tanaka Y, Yasui K, Hayashi H, Matsuyama T:Gamma-interferon-inducible, lysosome/endosome-localized thiolreductase, GILT, has anti-retroviral activity and its expression is counteracted by HIV-1.¸Oncotarget¸7.44.71255-71273¸2016/11
4 1. Izumida M, Kamiyama H, Suematsu T, Honda E, Koizumi Y, Yasui K, Hayashi H, Ariyoshi K, Kubo Y.:Fragments of Target Cells are Internalized into Retroviral Envelope Protein-Expressing Cells during Cell-Cell Fusion by Endocytosis.¸Front Microbiol¸6.1552.1-9¸2016/01
5 Kakoki K, Shinohara A, Izumida M, Koizumi Y, Honda E, Kato G, Igawa T, Sakai H, Hayashi H, Matsuyama T, Morita T, Koshimoto C, Kubo Y:Susceptibility of muridae cell lines to ecotropic murine leukemia virus and the cationic amino acid transporter 1 viral receptor sequences: implications for evolution of the viral receptor.¸Virus Genes¸¸2014/04
6 Shigematsu S, Hayashi H, Yasui K, Matsuyama T.:SAM domain- containing N-terminal region of SAMHD1 plays a crucial role in its stabilization and restriction of HIV-1 infection.¸Acta Med Nagasaki¸¸2014/04
7 Kakoki K, Kamiyama H, Izumida M, Yashima Y, Hayashi H, Yamamoto N, Matsuyama T, Igawa T, Sakai H, Kubo Y. :Androgen-independent proliferation of LNCaP prostate cancer cells infected by xenotropic murine leukemia virus-related virus. ¸Biochem Biophys Res Commun¸¸2014/04
8 Chua KJ, Kubo Y, Ma Y, Yasui K, Matsuyama T, and Hayashi H.:A short variant BTBD2 as a novel negative regulator of IRF-associated signalling.¸Int J Integrative Biol¸14.1.31-38¸2013/07
9 Kamiyama H, Kakoki K, Shigematsu S, Izumida M, Yashima Y, Tanaka Y, Hayashi H,:CXCR4-tropic, but not CCR5-tropic, human immunodeficiency virus infection is inhibited by the lipid raft-associated factors, acyclic retinoid analogs, and cholera toxin B subunit.¸AIDS Res Hum Retroviruses¸29.2.279-288¸2013/02
10 Kubo Y, Hayashi H, Matsuyama T, Sato H, Yamamoto N. :Retrovirus entry by endocytosis and cathepsin proteases.¸Adv Virol¸2012.640894¸2012/12
Research Activities, etc
Participation in Lectures and Seminars Organized by Private Bodies
1 Identification of poly(I:C)-induced pancreatitis- related genes in IRF2-deficient mice¸Third International Conference "Current advances in Microbiology and Immunology"¸2012/06
2 Search for Anti-inflammatory molecules¸Nagasaki-Singapore Symposium¸2008/10
Education Information
2017 (Fall, 2nd year of the MC¸1class/week )
2017 (Fall, 2nd year of the MC¸1class/week )
2017 (Fall, 2nd year of the MC¸1class/week )
2017 (Fall, 2nd year¸1class/week )
2017 (Fall, 2nd year¸1class/week )
2015 Cellular and Molecular Biology of Cancer (Fall, 2nd year¸2class/week ¸Contribution to teaching : 67.00%)
2014 Cellular and Molecular Biology of Cancer (Fall, 2nd year¸2class/week ¸Contribution to teaching : 53.00%)
2013 Cellular and Molecular Biology of Cancer (Fall, 2nd year)
2013 Biomedical Science (Others)
2013 Cellular and Molecular Biology of Cancer (Spring , 3rd year)
Others (Self promotion, etc.)