Detailed Information
Full Name ARUGA Jun Date of Birth
Affiliation Institute of Biomedical Sciences 
TEL +81-95-819-7043 FAX +81-95-7044
Job Title Professor Academic Degrees /
Qualifications
Doctor (Mecical Science)(1991/03)
Medical doctor(1987/08)
E-mail
Homepage http://www.med.nagasaki-u.ac.jp/phrmch1/ http://lcn.brain.riken.jp/index.html
Education 1987/03¸Tohoku University¸Faculty of Medicine¸Graduated
1991/03¸Tohoku University¸Graduate School, Division of Medicine¸Doctor Course¸Completed
Employment Experience 1991/04 - 1993/03¸Tokyo University, Institute of Medical Sciences¸Research Associate
1993/03 - 1999/07¸RIKEN Tsukuba Life Science Center¸Researcher
1999/07 - 2003/03¸RIKEN Brain Science Institute¸Researcher
2003/04 - 2003/12¸RIKEN Brain Science Institute¸Deputy Laboratory Head
2004/01 - 2013/05¸RIKEN Brain Science Institute¸Laboratory Head
2008/04 - 2013/03¸Saitama University Brain Science Institute¸Visiting Professor
2009/04 - 2013/03¸Waseda University, Faculty of Science and Engineering¸Visiting Professor
2013/06 - 2013/09¸RIKEN Brain Science Institute¸Researcher
Specialties General neuroscience¸Developmental biology¸General pharmacology
Academic Societies The Japanese Pharmacological Society (Councilor)¸Society for Neuroscience¸The Japanese Neuroscience Society¸The Molecular Biology Society of Japan
Awards
Committee Memberships
Ongoing Joint Research
Technical Supervision
Technical Consulting
Themes for Prospective Joint Research
Themes for Ongoing Research
Research Themes in the Past
Literary Works, Books, Writings and Research Papers, Art Works, Industrial Products, Software, Sports Records, etc.
1 Tohmonda T, Kamiya S, Ishiguro A, Iwaki T, Fujimi TJ, Hatayama M, Aruga J: Identification and characterization of novel conserved domains in metazoan Zic proteins¸Mol Biol Evol¸¸2018/06
2 Jun Aruga:Zic family - Evolution, Development and Disease.¸Springer¸2018/02
3 Morimura N, Yasuda H, Yamaguchi K, Katayama KI, Hatayama M, Tomioka NH, Odagawa M, Kamiya A, Iwayama Y, Maekawa M, Nakamura K, Matsuzaki H, Tsujii M, Yamada K, Yoshikawa T, Aruga J.:Autism-like behaviours and enhanced memory formation and synaptic plasticity in Lrfn2/SALM1-deficient mice.¸Nat Commun¸8.15800-¸2017/06
4 Tomioka NH, Yasuda H, Miyamoto H, Hatayama M, Morimura N, Matsumoto Y, Suzuki T, Odagawa M, Odaka YS, Iwayama Y, Um JW, Ko J, Inoue Y, Kaneko S, Hirose S, Yamada K, Yoshikawa T, Yamakawa K, Aruga J:Elfn1 recruits presynaptic mGluR7 in trans and its loss results in seizures. ¸Nat Commun¸5.4501-¸2014/07
5 Kabayama M, Sakoori K, Yamada K, Ornthanalai VG, Ota M, Morimura N, Katayama K, Murphy NP, Aruga J:Rines E3 Ubiquitin Ligase Regulates MAO-A Levels and Emotional Responses.¸J Neurosci¸33.12940-12953¸2013/08
6 Tekin M, Chioza BA, Matsumoto Y, Diaz-Horta O, Cross HE, Duman D, Kokotas H, Moore-Barton HL, Sakoori K, Ota M, Odaka YS, Foster II J, Cengiz FB, Tokgoz-Yilmaz S, Tekeli O, Grigoriadou M, Petersen MB, Sreekantan-Nair A, Gurtz K, Xia X-J, Pandya A, Patton MA, Young JI, Aruga J, Crosby AH:SLITRK6 mutations cause myopia and deafness in humans and mice.¸J Clin Invest¸123.5.2094-2102¸2013/04
7 Takahashi H, Katayama K-i, Sohya K, Miyamoto H, Prasad T, MatsumotoY, Ota M, Yasuda H, Tsumoto T, Aruga J, Craig AM.:Control of inhibitory synapse development by Slitrk3-PTPdelta trans-synaptic interaction.¸Nat Neurosci¸15.389-398¸2012/01
8 Katayama K-i, Yamada K, Ornthanalai VG, Inoue T, Ota M, Murphy NP, Aruga J:Slitrk1-deficient mice display elevated anxiety-like behavior and noradrenergic abnormalities.¸Mol Psychiatry¸15.2.177-184¸2010/02
9 Hatayama M, Tomizawa T, Sakai-Kato K, Bouvagnet P, Kose S, Imamoto N, Yokoyama S, Utsunomiya-Tate N, Mikoshiba K, Kigawa T, Aruga J:Functional and structural basis of the nuclear localization signal in the ZIC3 zinc finger domain, a role of conserved tryptophan residue in the zinc finger domain.¸Hum Mol Genet¸17.3459-3473¸2008/11
10 Inoue T, Ogawa M, Mikoshiba K, Aruga J:Zic deficiency in the cortical marginal zone and meninges results in cortical lamination defects resembling those in type II lissencephaly.¸J Neurosci¸28.18.4712-4725¸2008/04
Research Activities, etc
Patents
Participation in Lectures and Seminars Organized by Private Bodies
1 LRR synapse organizers in health and diseases¸日本解剖学会全国学術集会¸2017/03
Education Information
Others (Self promotion, etc.)